Run a systematic review from one prompt

A SciSpace agent can draft PICO questions, search papers, screen them, extract data, and assemble a review with a PRISMA diagram.

Done with Custom agentยท Advancedยท Apr 2026

What they did
A user started with a single prompt on scispace.com. The agent first turned the topic into PICO-style questions and screening rules, then let the user edit those and choose databases and date ranges. After that, it searched across databases, sorted the results again, screened titles and abstracts, checked full texts, downloaded PDFs, pulled out data, and built the review plus a PRISMA diagram and inclusion table.
How it went
It produced a full systematic review and PRISMA diagram from one prompt. Papers that sit behind paywalls still stopped the process from being completely automatic.
Tips
This works best when the user reviews the inclusion criteria before screening begins. Expect to handle any paywalled articles manually.

Try it yourself with ChatGPT Agent

Help me run a systematic review on [research question]. First, draft PICO-style questions and proposed inclusion/exclusion rules, then pause and ask me to confirm or edit them before you screen anything. After I approve, search these sources: [databases] within [date range], screen titles/abstracts and then full texts against the approved criteria, extract these data fields: [data points], and compile the findings into a written review, an inclusion table, and a PRISMA-style flow summary showing how many records were found, screened, excluded, and included. If you hit a paywalled paper, flag it and stop before making any irreversible action or skipping it without my approval.

Fill in the [brackets]. Agents can make mistakes, so review anything before it is sent, paid or deleted.

Read the original on x.com โ†—

1 more report of this

Get 3 agent uses like this every morning

With the day's top AI news. Free, and one click to unsubscribe.